Thursday 20 February 2014

Insulin theory - myth busted

On the internet, I see a lot of arguments that go like this;

Carbohydrates are bad for you because they cause your body to release insulin. Insulin is a hormone which stores fat and stops you burning fat. Therefore, if you are storing fat and not burning it, you get fat. Therefore, carbohydrates make you fat. 

 

sounds plausible.... here’s why it’s bullshit.


In order to gain weight, we have to store more energy than we burn; this is a fact we cannot deny. But insulin theorists seem to think that this hormone can bypass the laws of physics and create energy out of nowhere. Let’s look at the logic behind this.



Person A

Person A eats a meal of pure carbohydrate at 800 calories, their insulin raises. Imagine a worst case scenario where ALL OF IT gets quickly stored as fat (this would not happen anyway, as a large majority would be stored as glycogen, or burned off on the spot). Even in a worst case scenario, they can only store 800 calories of energy as fat. THEY CANNOT STORE MORE ENERGY THAN THIS.

Person A



Now, once that meal has digested, the blood sugars have dropped (because it has all been turned into fat), insulin levels drop and fat burning increases again. If the person needs a total of 2000 calories in a day for their metabolic rate, they have to get that energy from somewhere – which will now be fat stores (or glycogen stores too, if any of that carbohydrate was stored away in this form). So, Person A may have stored 800 calories, but then he has to get 2000 calories back out of the fat stores.

Net result – minus 1200 calories

Person B

Person B is our low carb Zealot. They hate insulin, so do everything they can to stay in an insulin free state (not possible, as we all have baseline insulin levels). This person eats 800 calories, but in the form of pure fat. But they think they are not storing any fat because they haven’t got any insulin running around in their body, right?
PersonB

Even if they were right (which they are not, there are other hormones in the body which store fat too), let’s look at what will happen. If the body is not storing the ingested 800 calories of fat, it will have to burn it from the blood. Their metabolism is 2000 calories per day also, so their body gets 800 of this from the ingested fat, and the other 1200 from fat stores. 


But even in this example where NO fat was stored and ONLY fat was used as fuel, the person still ends up only in 1200 calories deficit.


And this was the extreme example

This was giving full benefit of the doubt to the ‘insulin theorists’ also. In real life, most ingested carbohydrate gets burned off on the spot (one of the main actions of insulin is to tell the body to switch to higher blood glucose oxidation) so less can be stored as fat. Most of the excess which is above and beyond oxidation rates get stored as Glycogen, not fat, in the liver and muscle. This means that, with our 800 calories carb meal, almost none of it would get stored as fat.

Even when we increase the calories, the math stays the same.

On top of this, studies have shown that it takes an incredible amount of carbohydrate ingestion to see any amount of de novo lipogenesis (fat creation from glucose). It is much more likely that the glucose will be used for metabolic purposes or stored as glycogen before any fat is created. After all, energy is lost when our body makes fat out of glucose. This is not evolutionary advantageous (it would be better to be as energy efficient as possible).

This is also not evolutionary advantageous 


Insulin Action

To look at insulin and say that it is a fat storing hormone, and fat burning suppressor, is only half the story, and doesn’t make us fat anyway, as the last examples illustrated. Insulin has several roles, many of which are designed to let the body know there is carbohydrate in the blood stream, and to switch to burning this off in whatever way possible (increased oxidation, glycogen creation and fat storage) to lower blood sugars to normal levels. This is why insulin correlates so highly with blood sugar levels/carbohydrate intake.#

Insulin action


Insulin also serves as a break for endogenous glucose production. When our body is in a fasted state, we produce our own blood glucose (barring hypoglycemics) through gluconeogenesis (conversion of proteins to blood sugar) and conversion of glycogen to glucose. This keeps our blod sugars relatively stable postprandially. But this internal sugar production is not necessary when we have ingested carbohydrates. So insulin is a messenger to tell our body to stop creating its own sugar.

Anyway, insulin doesn’t just put a halt on fat burning. People see things so black and white these days. Our bodies are constantly burning and storing fat, building and breaking down muscle etc. It is the balance at the end of all of this which counts. Add to this, fat burning is not an on/off switch. Increases in insulin simply lower the percentage of fat which is utilised for metabolic purposes, but does not switch it off. The whole point is to just shift around what source you are using predominantly for fuel. How much you use/store will determine your balance at the end of the day, which will determine whether your body is building up (building fat/muscle) or catabolising (losing fat/muscle).

What most low carbers also don't realise is that even low carb diets can produce blood sugar through an act called gluconeogenesis. Protein gets broken down into sugars and can be used as fuel. Some extremists, like LCHF dieters, even lower protein intake to get around this. but there is no getting around the laws of thermodynamics - as my examples showed (one was high carb, the other was Low carb high fat).

Ans some non-carb foods can raise as much insulin as standard carbohdyrate rich foods.

But my low carb diet works

Great,  that’s good for you. It can work, I am not denying that. But low carb diets work as a result of controlling calories indirectly. Eating less carbs results in eating more protein and fat – which are very satiating (and is why I recommend keeping fat in your diet, and eating high levels of protein).



But most of the differences in scientific studies comparing diets of different macronutrients (in equicaloric statuses) can be put down to


·         Difference in protein intake (protein is thermogenic and loses more calories in the body)
·         Bigger water losses through lost glycogen (we store an incredible amount of water in our bodies)
·         Lower gut bulk (low carb diets tend to be less fibrous and more energy dense).

And as Dr John Berardi recently pointed out HERE, the cascade of hormonal events happening on a low carb diet can serve to lower performance in athletes, and see a drop in muscle mass as a result of lower glycogen stores, lower insulin (insulin is muscle sparing) and lowered training volume. Also, testosterone to cortisol ratios go out of whack in the long term – not great for muscle building/maintaining. 





I will say, however, this can be offset by low carb diets having larger amounts of protein. But it would be better to have a high protein diet and include enough carbs to reduce the negative effects, without adding too many calories.


And while low carb diets do work well for most (especially in the first couple of weeks, due to the massive drops in water weight), they can be difficult to sustain for the majority of folk. Real success in dieting is having the ability to maintain that diet for life. Ask yourself this – is low carb something you can really do for life?

Summary

Insulin does not cause you to get fat. Insulin has many actions, but it can only make you as fat as the energy you bring in to the system.

Insulin has many actions – making us fat is not one of them.

Low carb diets may not suit all, especially athletes.


As an important note, I am not anti-low carb. There can be several benefits to low carb. Increased satiation, increased fat intake, increased protein intake and better blood glucose control are just some. This post is more an attack on the insulin theory of obesity.

Monday 3 February 2014

Rebuttal against a 'Calories don't count' argument

This is a rebuttal to the article floating around on the net about how calories don't count. Take a read, you may be convinced.

CLICK HERE TO READ THE ARTICLE FIRST

The Rebuttal

Below are a list of the pictures from the article, along with my reasons for why they do not disprove the calorie in versus out argument for weight gain.


 1. Injecting insulin will change where fat is stored not HOW MUCH. This is also not how insulin works in a human body in a non-injected state, where it would be more generalised. Regardless, insulin doesn't create extra energy storage, just changes its location.








2. Going have to semi-bow out of this one as I know nothing about Cushins. Although so what - if you don't have Cushins disease, then this doesn't apply.









3. The guy is obviously one of those people who has a very reactive metabolism - they do exist. I know a lot of people with these genetics who are the same. If they eat a hell of a lot more calories, their metabolism raises to almost match it.

This doesn't disprove calories in vs out or make it irrelevant. If this guy wanted to gain weight, he would have to eat more - far more, as his metabolism ramps up more than normal. If he wanted to lose weight, he would just have to eat less.

The same principles apply to everyone. You have to find out your own personal numbers. Personally, if I am looking to gain 1lb a week, I eat around 3000 calories, and if it is not working, I eat MORE until I am gaining 1lb a week. IF I want to lose weight, I eat around 1,800 a day to lose around 1lb a week. If that doesn't work, I exercise a little more. But I am patient with it as I know water weight fluctuates.

If you are not fortunate enough to have his genetics, you would have to find out how much YOU need to eat to gain a certain amount of weight/lose it. It's not always going to be a static number, but if you are not losing weight you should find a way of getting less energy in, or getting more energy out.

Also - with this guy, it was only n=1 and also only 3 weeks. In 3 weeks it would be possible to lose 5-6 pounds of water weight from glycogen stores, another couple of pounds of gut bulk and still gain fat. You can, for short periods of time like this, be gaining fat whilst the scale is going down. Let him try that for a full year and see how it works out.



4. Again, a case of genetic/disease related change in WHERE the fat is stored, not HOW MUCH. The amount of energy stored in the system hasn't been influenced, only the site of that storage. So again, doesn't mean calories are valueless (confused look as to why anyone would think it does).










5. see above


6. So what!!! Sure, low carb diets may have some role for SOME PEOPLE in regulating energy intake, as
in anorexics may start eating more energy and obese may start eating less energy. Doesn't mean they are the best diets for everyone and doesn't discredit counting calories, or portion control (or whatever method you wish to choose to use in order to regulate energy intake).

Low carb is not always the best way for everyone, even if I would conclude that it is a relatively good way for most people to go. For me, personally, it would be torturous hell - and science has shown that it doesn't provide a significant amount more of weight loss above and beyond what simple water loss (through glycogen depletion) would provide - along with potential muscle losses from the lower amount of insulin and lower muscle glycogen storage (that's right, insulin preserves muscle).


7. Read http://weightology.net/?p=265





8. The whole body is a calorie receptor. It responds to calories by increasing and decreasing certain hormones which can increase metabolism, change substrate oxidation and decrease amounts of food desired (satiation qualities). Leptin, Ghrelin, Insulin, HGH, IGF1, Cortisol, glucagon, adiponectin, thyroid etc etc etc - all respond to caloric intake.


Does changing what you eat have an effect on energy out and (indirectly) energy in? Sure, it can do. But it is usually not as large an effect as you think, and by NO MEANS discredits the use of calorie control exercises through direct means (calorie counting) or indirect (portion control, eating more satiating foods etc).

Fact is, if you eat the same foods but a higher quantity of them, you will gain more weight, and if you eat the same foods in lower quantities you will lose weight/gain less.


9. Umm, yes, not all macronutrients behave the same way in the body. Some have higher thermic effects and so calories are lost in the process of breaking it down. However, this doesn't violate the idea that calories count. It still applies that calories in vs out will determine how much energy is in the system. Thermic effect simply increases the 'energy out' side of the equation.

Anyway, to conclude that getting rid of carbohydrates is wrong. It is clearly biased towards a low carb diet for no reason at all. The whole reason the diet produces a lower caloric yield if we replace 55% carbs with equal amounts fat and protein is not due to the lower carb, it is due to the increase in PROTEIN, which has the highest thermic effect.

In fact, one could say that replacing fat with equal parts protein and carbs (I do not recommend) would produce a lower caloric yield still, as Fat has the lowest thermic effect of all.


Bottom line

The bottom line is, calories count, whether you count them or not. You could cut your calories in by cutting out an entire food group/macronutrient. But this usually leaves people craving what they have cut, leading to an eventual falling off the wagon. You could also use portion control, or count calories consciously, which could offer you more freedom in what you eat. But the idea that calories don't count is ludicrous, and wrong, as every scientific study EVER has shown.

Everyone responds to foods differently. Some can gain weight easily with a small excess, some can have a massive excess and still burn it off with their very reactive metabolisms. But the overall principle remains the same. If you want to get smaller, eat less of what you do. If you want to get bigger, eat more of what you do now. Use exercise as a way of improving health and energy expenditure.

The one which annoys me most is the insulin theory. The idea that insulin makes you gain weight. Well, guess what. If I pump my blood full of insulin and don't eat a thing, you can be sure I wont be gaining weight. Even if I ate 500 calories with my 'insulin blood', it is only possible to store 500 calories of fat (and that is if there was a 100% efficient conversion, which there is not).

For those who say, "Yeah, but if you had insulin in your blood and no glucose, you would go into a hypoglycaemic coma" - you are right. So the type 2 diabetics with high insulin levels must be using something for fuel. If they are using lower amounts of fat, that must mean they are using higher amounts of blood glucose (which makes sense as the blood glucose for type 2 diabetics is high). If more blood glucose is burned as fuel, less can be stored as fat, and thus the law of calories in vs out returns as the king.


Take home advice

The best pieces of advice I can give are;

1. Increase your PROTEIN intake (but there is a law of diminishing returns).
2. Find out how many calories YOU need to manipulate your weight in the direction you want.
3. keep a healthy balance of fats and carbs in your diet.
4. Eat an overall higher amount of MICRONUTRITION through better food choices, but don't feel you have to cut out what you love.
6. Don't do too much cardio when you are on a restricted calorie diet. In fact, cardio is completely unnecessary when trying to lose fat. But if you like to do it, go ahead.
7. Eat foods that curb your hunger. Usually low calorie density foods like veggies will do this as well as fulfilling number 4. But find out what works for you.
8. Don't CRASH DIET. 1/2 a pound a week is still 26 pounds of weight loss a year. We all know that person who loses 20lb every time they diet, yet ironically weigh more and more each year.